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Structure of 1364932-19-3
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The standard in situ coupling reagent for solid phase peptide synthesis [1,2,3,4,5]. This product can replace BOP in all applications without loss of performance. Unlike uronium-based reagents, PyBOP does not give rise to guanidinated by-products during cyclization and fragment condensation reactions.Associated Protocols and Technical ArticlesGuide to Selection of Coupling Reagents Literature references [1] J. Martinez, et al. (1985) J. Med. Chem., 28, 1874.[2] J. Coste, et al. (1990) Tetrahedron Lett., 31, 205.[3] G. B. Fields, et al. in Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 241.[4] T. Heg-Jensen, et al. (1991) Tetrahedron Lett., 32, 7617.[5] R. von Eggelkraut-Gottanka, et al. (2003) Tetrahedron Lett., 44, 3551.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: