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N-Methylpyrrolidine-3-carboxamide hydrochloride

  • CAS No. 1361115-18-5

  • Cat. No. CS-0188103
  • Molecule weight164.63
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Methylpyrrolidine-3-carboxamide hydrochloride|CS-0188103

Structure of 1361115-18-5

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General Information

  • CAS No. 1361115-18-5
  • Cat. No. CS-0188103
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃ClN₂O
  • Molecular Weight 164.63
  • Synonym(s) N-Methyl-3-pyrrolidinecarboxaMide HCl
  • SMILES CNC(C1CCNC1)=O.Cl

Description

N-Methylpyrrolidine-3-carboxamide hydrochloride features a pyrrolidine core with a methylated amide functionality, delivering enhanced solubility and stability under standard conditions. The hydrochloride salt form ensures improved crystallinity and handling ease, making it well-suited for synthetic applications in medicinal chemistry and peptide analog development.

Application

N-Methylpyrrolidine-3-carboxamide hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and peptidomimetics. Its amide functionality offers enhanced metabolic stability and favorable solubility, while the N-methylated pyrrolidine ring provides conformational rigidity and improved membrane permeability. The hydrochloride salt ensures excellent bench stability and ease of handling, facilitating straightforward purification and integration into multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   41.13
  • LogP   -0.2363
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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