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CS-W001157 4
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Phenyl propargyl ether

  • CAS No. 13610-02-1

  • Cat. No. CS-0146740
  • Purity≥97%
  • MDL No.MFCD00048107

*For research and further manufacturing use only, not for direct human use.

Phenyl propargyl ether|CS-0146740

Structure of 13610-02-1

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General Information

  • CAS No. 13610-02-1
  • Cat. No. CS-0146740
  • Purity ≥97%
  • MDL No. MFCD00048107
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O
  • Molecular Weight None
  • Synonym(s) Phenyl prop-2-yn-1-yl ether
  • SMILES C#CCOC1=CC=CC=C1

Description

Phenyl propargyl ether features a robust propargyl linkage that enables seamless integration into click chemistry workflows. The aromatic phenyl group enhances stability and solubility in organic media, while the terminal alkyne supports efficient copper-catalyzed azide-alkyne cycloaddition. This compound serves as a reliable building block for synthesizing functionalized polymers and bioconjugates under standard conditions.

Application

Phenyl propargyl ether serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized alkynes and heterocyclic scaffolds. Its robust bench stability and compatibility with copper-catalyzed azide-alkyne cycloaddition (CuAAC) facilitate reliable click chemistry applications. The molecule functions as a protected phenolic synthon and undergoes selective transformations under mild conditions, supporting diverse downstream modifications in medicinal chemistry and materials synthesis.

Synthesis

  • Route1
    • null|null
      106-96-7
    • null|null
      108-95-2
    • ~99%
    • In-stock
      Phenyl propargyl ether|CS-0146740
      13610-02-1

    References

    • Banday, Abid H.; Shameem, Shameem A.; Gupta; Kumar, H.M. Sampath Steroids, 2010 , vol. 75, # 12 p. 801 - 804
  • Route2
    • null|null
      107-19-7
    • null|null
      108-95-2
    • ~84%
    • In-stock
      Phenyl propargyl ether|CS-0146740
      13610-02-1

    References

    • Subramanian, R. Sankara; Balasubramanian, K. K. Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1255 - 1260
  • Route3
    • null|null
      56-23-5
    • null|null
      107-19-7
    • ~46%
    • In-stock
      Phenyl propargyl ether|CS-0146740
      13610-02-1

    References

    • Nippon Paint Co., Ltd. Patent: US5340931 A1, 1994 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3272
Class : 3
Packing Group : Ⅱ
Hazard Statements : H227-H315-H318-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.6986
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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