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Structure of 13600-48-1
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2-Chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the chloro and methyl substituents fine-tune reactivity. This electron-deficient heterocycle serves as a key intermediate in agrochemical and pharmaceutical synthesis, offering robust performance under standard conditions.
2-Chloro-6-methyl-4-(trifluoromethyl)nicotinonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocyclic scaffolds. Its trifluoromethyl and nitrile groups provide strong electron-withdrawing character, facilitating nucleophilic substitution and transition-metal-catalyzed coupling reactions. The chloro and methyl substituents offer orthogonal reactivity for selective derivatization, while the compound exhibits good bench stability and ease of purification—ideal for modular synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: