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Structure of 1354951-84-0
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Benzyl (4-aminobicyclo[2.1.1]hexan-1-yl)carbamate hydrochloride features a rigid bicyclic scaffold with a primary amine at the 4-position, enabling direct functionalization or salt formation. The benzyl carbamate group provides stability and facilitates controlled deprotection under mild conditions. This compound serves as a key intermediate in the synthesis of conformationally restricted biologically active molecules.
Benzyl (4-aminobicyclo[2.1.1]hexan-1-yl)carbamate hydrochloride serves as a versatile, bench-stable building block for the synthesis of nitrogen-containing heterocycles and bioactive molecules. The bicyclo[2.1.1]hexane core imparts conformational rigidity and metabolic stability, while the protected amine enables selective functionalization. Its hydrochloride salt form enhances solubility and purification ease, facilitating use in standard coupling reactions, reductive amination, and peptide extension workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: