2-Methoxyquinolin-7-amine

Name: 2-Methoxyquinolin-7-amine
Brand: ChemScene
Availability: OutOfStock
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CAS No. 1354222-16-4
Cat. No. CS-0150343
Purity≥97%
MDL No.MFCD22394145

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 1354222-16-4

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Description

2-Methoxyquinolin-7-amine delivers a strategically positioned methoxy group and primary amine at the 7-position, enabling direct functionalization in medicinal chemistry. This electron-rich scaffold integrates readily into kinase inhibitors and fluorescent probes, offering enhanced solubility and metabolic stability under standard conditions.

Application

2-Methoxyquinolin-7-amine serves as a versatile building block for the synthesis of quinoline-based pharmaceuticals and functional materials. Its amine functionality enables facile derivatization via amidation, alkylation, and transition-metal-catalyzed coupling reactions. The methoxy group enhances solubility and modulates electronic properties, while the scaffold exhibits bench stability and compatibility with standard purification techniques.

General Information

CAS No. 1354222-16-4
Cat. No. CS-0150343
Purity ≥97%
MDL No. MFCD22394145
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₀N₂O
Molecular Weight 174.20
Synonym(s) 7-Amino-2-methoxyquinoline
SMILES COC1=CC=C2C=CC(=CC2=N1)N

Computational Chemistry Data

TPSA 48.14
LogP 1.8256
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

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2-Methoxyquinolin-7-amine

CAS No. 1354222-16-4

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