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CS-W001157 4
Total: USD 88.00

4-Bromo-2-chloropyridin-3-amine

  • CAS No. 1354021-09-2

  • Cat. No. CS-0042697
  • Molecule weight207.46
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-chloropyridin-3-amine|CS-0042697

Structure of 1354021-09-2

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General Information

  • CAS No. 1354021-09-2
  • Cat. No. CS-0042697
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrClN₂
  • Molecular Weight 207.46
  • Synonym(s) 4-bromo-2-chloro-pyridin-3-amine
  • SMILES NC1=C(Br)C=CN=C1Cl

Description

4-Bromo-2-chloropyridin-3-amine serves as a critical building block in medicinal chemistry, featuring a heteroaromatic core with orthogonal halogen handles. This scaffold enables selective cross-coupling and functionalization under standard conditions, facilitating rapid diversification in drug discovery campaigns.

Application

4-Bromo-2-chloropyridin-3-amine serves as a versatile building block in medicinal chemistry and process development, enabling efficient construction of nitrogen-containing heterocycles. Its dual halogen substituents facilitate palladium-catalyzed cross-coupling reactions, while the primary amine group supports derivatization via acylation, alkylation, or cyclization. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, making it ideal for modular synthesis of pharmaceutical intermediates and functionalized pyridine scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.0797
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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