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Structure of 1353973-60-0
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6-Chloro-N-methyl-2-(methylsulfonyl)pyrimidin-4-amine features a chlorinated pyrimidine core paired with a methylsulfonyl group, enabling selective reactivity in cross-coupling and medicinal chemistry applications. The N-methyl substitution enhances solubility and metabolic stability, while the electron-withdrawing sulfonyl moiety directs regioselective functionalization under mild conditions.
6-Chloro-N-methyl-2-(methylsulfonyl)pyrimidin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chlorine at C6 facilitates nucleophilic substitution, while the N-methyl and methylsulfonyl groups provide orthogonal functional handles for further derivatization. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, simplifying purification and integration into multi-step syntheses of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: