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CS-W001157 4
Total: USD 88.00

6-Methyl-2,6-diazaspiro[3.4]octane

  • CAS No. 135380-24-4

  • Cat. No. CS-0000665
  • Purity≥95%
  • MDL No.MFCD08234739

*For research and further manufacturing use only, not for direct human use.

6-Methyl-2,6-diazaspiro[3.4]octane|CS-0000665

Structure of 135380-24-4

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General Information

  • CAS No. 135380-24-4
  • Cat. No. CS-0000665
  • Purity ≥95%
  • MDL No. MFCD08234739
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄N₂
  • Molecular Weight 126.20
  • Synonym(s) 6-Methyl-2,6-diazaspiro[3.4]octane oxalate
  • SMILES CN1CC2(CNC2)CC1

Description

6-Methyl-2,6-diazaspiro[3.4]octane features a rigid spirocyclic core with strategically positioned nitrogen atoms and a methyl substituent that enhances lipophilicity and conformational stability. This scaffold delivers enhanced metabolic resistance and favorable binding kinetics in medicinal chemistry applications.

Application

6-Methyl-2,6-diazaspiro[3.4]octane serves as a rigid, bicyclic scaffold for medicinal chemistry applications, offering enhanced conformational control and metabolic stability. The spirocyclic framework provides orthogonal nitrogen sites for derivatization, while the methyl group at C6 improves solubility and steric profile. This compound enables efficient access to diverse heterocyclic architectures through standard functionalization protocols, facilitating rapid library synthesis in lead optimization campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H314-H335
Precautionary Statements : P210-P260-P261-P270-P271-P280-P301+P330+P331-P304+P340-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   -0.0885
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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