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Structure of 1353584-74-3
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2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine is a boronate ester-functionalized heterocycle featuring a sterically shielded diborane moiety. This bench-stable reagent integrates readily into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides under mild conditions. The electron-deficient imidazopyridazine core enhances reactivity while the tetramethyl-substituted dioxaborolane group ensures excellent stability and solubility in common organic solvents.
2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. Its imidazo[1,2-b]pyridazine core provides a rigid, electron-deficient heterocyclic scaffold with demonstrated utility in medicinal chemistry and materials science. The stable, bench-ready boronate moiety enables efficient coupling with aryl, vinyl, and acyl halides under mild conditions, offering high functional group tolerance and reliable yields in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: