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CS-W001157 4
Total: USD 88.00

6,7-Dihydroisoquinolin-8(5H)-one hydrochloride

  • CAS No. 135311-97-6

  • Cat. No. CS-W022438
  • Purity≥96%
  • MDL No.MFCD18432614

*For research and further manufacturing use only, not for direct human use.

6,7-Dihydroisoquinolin-8(5H)-one hydrochloride|CS-W022438

Structure of 135311-97-6

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General Information

  • CAS No. 135311-97-6
  • Cat. No. CS-W022438
  • Purity ≥96%
  • MDL No. MFCD18432614
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀ClNO
  • Molecular Weight 183.64
  • Synonym(s) 8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride
  • SMILES O=C1CCCC2=C1C=NC=C2.[H]Cl

Description

6,7-Dihydroisoquinolin-8(5H)-one hydrochloride features a rigid, electron-rich heterocyclic core with enhanced solubility and stability under standard conditions. This bench-stable scaffold integrates readily into medicinal chemistry campaigns, serving as a key building block for bioactive alkaloid analogs and CNS-targeted compounds.

Application

6,7-Dihydroisoquinolin-8(5H)-one hydrochloride serves as a stable, bench-ready building block for the synthesis of isoquinoline-based pharmaceuticals and bioactive heterocycles. Its amide functionality enables direct functionalization or coupling reactions, while the hydrochloride salt enhances solubility and crystallinity for purification. This scaffold is well-documented in medicinal chemistry for its role in constructing core structures of kinase inhibitors and CNS-targeted agents.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.0224
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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