6-Bromo-5-chloroimidazo[1,2-a]pyridine

Name: 6-Bromo-5-chloroimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 1352898-81-7
Cat. No. CS-0050263
Purity≥97%
MDL No.MFCD22552935

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-5-chloroimidazo[1,2-a]pyridine|CS-0050263

Structure of 1352898-81-7

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Description

6-Bromo-5-chloroimidazo[1,2-a]pyridine features a fused heterocyclic core with complementary halogenation at the 6-bromo and 5-chloro positions, enabling selective cross-coupling reactions. This electron-deficient imidazopyridine scaffold integrates readily into complex molecular architectures under palladium-catalyzed conditions, offering precise control in medicinal chemistry and materials synthesis.

Application

6-Bromo-5-chloroimidazo[1,2-a]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its dual halogenation pattern enables sequential cross-coupling reactions, facilitating the construction of complex biaryl and triaryl scaffolds. The molecule exhibits excellent bench stability, ease of handling, and compatibility with palladium-catalyzed coupling protocols such as Suzuki-Miyaura and Buchwald-Hartwig reactions. Functional group tolerance supports efficient late-stage derivatization in synthetic workflows.

General Information

CAS No. 1352898-81-7
Cat. No. CS-0050263
Purity ≥97%
MDL No. MFCD22552935
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrClN₂
Molecular Weight 231.48
Synonym(s) 6-Bromo-5-chloro-imidazo[1,2-a]pyridine
SMILES ClC1=C(Br)C=CC2=NC=CN12

Computational Chemistry Data

TPSA 17.3
LogP 2.7502
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-5-chloroimidazo[1,2-a]pyridine

CAS No. 1352898-81-7

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