(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine

Name: (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 135248-89-4
Cat. No. CS-0101054
Purity≥97%
MDL No.MFCD03788178

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine|CS-0101054

Structure of 135248-89-4

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General Information

CAS No. 135248-89-4
Cat. No. CS-0101054
Purity ≥97%
MDL No. MFCD03788178
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₁₇NO₄S
Molecular Weight 343.40
Synonym(s) None
SMILES SC[C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

Cleavable Fmoc-L-cysteine for solid-phase peptide synthesis, featuring a benzyl-protected thiol group and a labile carbamate linkage. This derivative enables efficient incorporation of cysteine residues with orthogonal deprotection compatibility, supporting disulfide bond formation in complex peptide architectures under standard conditions.

Synthesis

Route1
- In-stock
  
  135273-01-7
- ~91%
- In-stock
  
  135248-89-4
References
- Han, Yongxin; Barany, George Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3841 - 3848
Route2
- In-stock
  
  103213-32-7
- ~99%
- In-stock
  
  135248-89-4
References
- Postma, Tobias M.; Albericio, Fernando; Giraud, Matthieu Organic Letters, 2012 , vol. 14, # 21 p. 5468 - 5471,4 Title/Abstract Full Text Show Details Postma, Tobias M.; Giraud, Matthieu; Albericio, Fernando Organic Letters, 2012 , vol. 14, # 21 p. 5468 - 5471
Route3
- 52-90-4
- 1131148-55-4
- ~69%
- In-stock
  
  135248-89-4
References
- Ibrahim, Tarek S.; Tala, Srinivasa R.; El-Feky, Said A.; Abdel-Samii, Zakaria K.; Katritzky, Alan R. Chemical Biology and Drug Design, 2012 , vol. 80, # 2 p. 194 - 202

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 75.63
LogP 2.9081
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 5

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Cysteine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine

CAS No. 135248-89-4

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