(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol

Name: (3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1350734-61-0
Cat. No. CS-0053305
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol|CS-0053305

Structure of 1350734-61-0

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Description

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol features a stereochemically defined pyran ring with adjacent amine and hydroxyl groups, enabling precise incorporation into chiral synthetic intermediates. This bench-stable scaffold delivers high diastereoselectivity in glycosylation and cyclization reactions, supporting efficient access to complex carbohydrate architectures and bioactive heterocycles under standard conditions.

Application

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol serves as a valuable chiral building block in medicinal chemistry, enabling efficient access to tetrahydropyran-containing scaffolds prevalent in bioactive molecules. Its well-defined stereochemistry and complementary functional groups—primary amine and secondary alcohol—facilitate selective transformations, including amide coupling, protection sequences, and cyclization reactions. The compound exhibits excellent bench stability and is readily purified by standard techniques, supporting its use in both small-molecule synthesis and process development workflows.

General Information

CAS No. 1350734-61-0
Cat. No. CS-0053305
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁NO₂
Molecular Weight 117.15
Synonym(s) None
SMILES N[C@@H]1COCC[C@H]1O

Computational Chemistry Data

TPSA 55.48
LogP -0.9051
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydropyran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol

CAS No. 1350734-61-0

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