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CS-W001157 4
Total: USD 88.00

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol

  • CAS No. 1350734-61-0

  • Cat. No. CS-0053305
  • Molecule weight117.15
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol|CS-0053305

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General Information

  • CAS No. 1350734-61-0
  • Cat. No. CS-0053305
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) None
  • SMILES N[C@@H]1COCC[C@H]1O

Description

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol features a stereochemically defined pyran ring with adjacent amine and hydroxyl groups, enabling precise incorporation into chiral synthetic intermediates. This bench-stable scaffold delivers high diastereoselectivity in glycosylation and cyclization reactions, supporting efficient access to complex carbohydrate architectures and bioactive heterocycles under standard conditions.

Application

(3R,4R)-3-Aminotetrahydro-2H-pyran-4-ol serves as a valuable chiral building block in medicinal chemistry, enabling efficient access to tetrahydropyran-containing scaffolds prevalent in bioactive molecules. Its well-defined stereochemistry and complementary functional groups—primary amine and secondary alcohol—facilitate selective transformations, including amide coupling, protection sequences, and cyclization reactions. The compound exhibits excellent bench stability and is readily purified by standard techniques, supporting its use in both small-molecule synthesis and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.48
  • LogP   -0.9051
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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