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CS-W001157 4
Total: USD 88.00

Tos-Phe-OH

  • CAS No. 13505-32-3

  • Cat. No. CS-0153039
  • Purity≥98%
  • MDL No.MFCD00037251

*For research and further manufacturing use only, not for direct human use.

Tos-Phe-OH|CS-0153039

Structure of 13505-32-3

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General Information

  • CAS No. 13505-32-3
  • Cat. No. CS-0153039
  • Purity ≥98%
  • MDL No. MFCD00037251
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₇NO₄S
  • Molecular Weight None
  • Synonym(s) Tosyl-L-phenylalanine
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O

Description

Tos-Phe-OH features a para-toluenesulfonyl (Tos) group appended to a phenylalanine-derived hydroxyl moiety, enabling stable conjugation in peptide synthesis. This derivative integrates seamlessly into C-terminal functionalization workflows, offering enhanced solubility and resistance to racemization under standard coupling conditions.

Synthesis

  • Route1
    • L-Phenylalanine Aspartame Impurity|CS-0229723
      63-91-2
    • null|null
      98-59-9
    • ~95%
    • In-stock
      Tos-Phe-OH|CS-0153039
      13505-32-3

    References

    • Saravanan; Sadhukhan, Arghya; Khan, Noor-Ul H.; Kureshy, Rukhsana I.; Abdi, Sayed H. R.; Bajaj, Hari C. Journal of Organic Chemistry, 2012 , vol. 77, # 9 p. 4375 - 4384
  • Route2
    • null|null
      591-51-5
    • null|null
      88452-86-2
    • ~57%
    • In-stock
      Tos-Phe-OH|CS-0153039
      13505-32-3

    References

    • Beresford, Kenneth J. M.; Church, Nicola J.; Young, Douglas W. Organic and Biomolecular Chemistry, 2006 , vol. 4, # 15 p. 2888 - 2897
  • Route3
    • null|null
      918886-05-2
    • ~10%
    • null|null
      69169-68-2
    • In-stock
      Tos-Phe-OH|CS-0153039
      13505-32-3

    References

    • Tetrahedron, , vol. 62, # 51 p. 11955 - 11962

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.47
  • LogP   1.96922
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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