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Structure of 13504-86-4
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This chiral pyrrolidine derivative features a bench-stable, moisture-tolerant hydroxyl group flanked by a protected carboxylic acid and benzylated nitrogen. The (2S,4S) stereochemistry enables precise incorporation into peptide backbones and complex heterocycles. Its solubility profile supports efficient coupling reactions under standard conditions, making it a reliable building block for medicinal chemistry campaigns targeting bioactive scaffolds.
(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive pyrrolidine-containing scaffolds. The hydroxyl group enables facile derivatization via esterification or ether formation, while the protected carboxylic acid allows for selective peptide coupling. Its bench-stable, crystalline nature and orthogonal functional group tolerance facilitate efficient incorporation into complex molecular architectures, including peptidomimetics and heterocyclic APIs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: