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CS-W001157 4
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5-Bromopyridin-2-ol

  • CAS No. 13466-38-1

  • Cat. No. CS-D0987
  • Purity≥95%
  • MDL No.MFCD00234042

*For research and further manufacturing use only, not for direct human use.

5-Bromopyridin-2-ol|CS-D0987

Structure of 13466-38-1

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General Information

  • CAS No. 13466-38-1
  • Cat. No. CS-D0987
  • Purity ≥95%
  • MDL No. MFCD00234042
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrNO
  • Molecular Weight 174.00
  • Synonym(s) None
  • SMILES O=C1C=CC(Br)=CN1

Description

5-Bromopyridin-2-ol delivers a reactive bromine site adjacent to a phenolic hydroxyl group, enabling efficient cross-coupling and functionalization under standard conditions. This bench-stable heterocycle integrates readily into synthetic sequences requiring orthogonal reactivity.

Synthesis

  • Route1

    References

    • ENDO PHARMACEUTICALS INC.; SMITH, Roger, Astbury; KETHIRI, Raghava, Reddy; KRISTAM, Rajendra; LAPING, Nicholas, James; VENKATESHAPPA, Chandregowda; KULKARNI, Bheemashankar; DEVRAJ, Rajesh; DEWANG, Purushottam Patent: WO2013/49559 A1, 2013 ; Location in patent: Page/Page column 67 ;
  • Route2
    • α-Pyridone Levetiracetam Impurity|CS-0213990
      142-08-5
    • ~55%
    • In-stock
      5-Bromopyridin-2-ol|CS-D0987
      13466-38-1

    References

    • Semple, Graeme; Andersson, Britt-Marie; Chhajlani, Vijay; Georgsson, Jennie; Johansson, Magnus; Lindschoten, Marcel; Ponten, Fritof; Rosenquist, Asa; Soerensen, Henrik; Swanson, Lars; Swanson, Marianne Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 197 - 200
  • Route3

    References

    • WO2013/49565 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   1.1374
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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