5-Bromo-6-methylimidazo[1,2-a]pyridine

Name: 5-Bromo-6-methylimidazo[1,2-a]pyridine
Brand: ChemScene
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CAS No. 1346157-13-8
Cat. No. CS-0163348
Purity≥98%
MDL No.None

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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5-Bromo-6-methylimidazo[1,2-a]pyridine|CS-0163348

Structure of 1346157-13-8

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General Information

CAS No. 1346157-13-8
Cat. No. CS-0163348
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) None
SMILES CC1=C(Br)N2C(C=C1)=NC=C2

Description

5-Bromo-6-methylimidazo[1,2-a]pyridine is a heterocyclic scaffold featuring a brominated imidazo[1,2-a]pyridine core with a methyl substituent at the 6-position. This electron-deficient, bench-stable framework serves as a key building block in medicinal chemistry for constructing bioactive molecules and functional materials.

Application

5-Bromo-6-methylimidazo[1,2-a]pyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle and electron-rich imidazopyridine core. The methyl group enhances regioselectivity in subsequent functionalizations and contributes to improved crystallinity and bench stability, facilitating straightforward isolation and purification. This scaffold is particularly valuable for constructing biologically relevant frameworks in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P304+P340

Quality Control

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Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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5-Bromo-6-methylimidazo[1,2-a]pyridine

CAS No. 1346157-13-8

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