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Structure of 1346148-32-0
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Methyl 5-fluoro-3-methylpicolinate is a fluorinated pyridine derivative featuring a methyl ester group at the picolinic acid core. This electron-deficient heterocycle integrates readily into synthetic routes requiring polar, stable intermediates. The para-fluoro and ortho-methyl substituents modulate reactivity and solubility, enabling efficient coupling in medicinal chemistry and materials synthesis under standard conditions.
Methyl 5-fluoro-3-methylpicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its ortho-substituted pyridine core offers enhanced stability and predictable reactivity in cross-coupling and nucleophilic substitution reactions. The methyl ester facilitates downstream derivatization, while the 5-fluoro and 3-methyl groups provide orthogonal functional handles for sequential modifications. Functions reliably in standard synthetic workflows requiring bench-stable, high-purity intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: