7-Chloro-1,6-naphthyridin-2(1H)-one

Name: 7-Chloro-1,6-naphthyridin-2(1H)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1345091-18-0
Cat. No. CS-0201415
Purity≥96%
MDL No.MFCD22548048

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Chloro-1,6-naphthyridin-2(1H)-one|CS-0201415

Structure of 1345091-18-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1345091-18-0
Cat. No. CS-0201415
Purity ≥96%
MDL No. MFCD22548048
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅ClN₂O
Molecular Weight 180.59
Synonym(s) 7-chloro-1H-1,6-naphthyridin-2-one
SMILES O=C1NC2=C(C=NC(Cl)=C2)C=C1

Description

7-Chloro-1,6-naphthyridin-2(1H)-one features a fused bicyclic core with a chlorinated position at C7 and a lactam functionality at N2, offering enhanced electron-withdrawing character. This scaffold integrates readily into pharmaceutical intermediates, enabling efficient access to kinase inhibitors and bioactive heterocycles under standard coupling conditions.

Application

7-Chloro-1,6-naphthyridin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its electrophilic C7-chlorine facilitates palladium-catalyzed cross-coupling reactions, while the 1,6-naphthyridin-2-one core offers hydrogen-bonding capacity and metabolic stability. The compound exhibits bench stability, moderate solubility, and compatibility with common protecting group strategies, making it well-suited for iterative synthesis and lead optimization workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 45.75
LogP 1.5765
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Naphthyridine compounds

Key Words

7-Chloro-1,6-naphthyridin-2(1H)-one sigma7-Chloro-1,6-naphthyridin-2(1H)-one manufacturer7-Chloro-1,6-naphthyridin-2(1H)-one price7-Chloro-1,6-naphthyridin-2(1H)-one structure7-Chloro-1,6-naphthyridin-2(1H)-one SDSbuy 7-Chloro-1,6-naphthyridin-2(1H)-one7-Chloro-1,6-naphthyridin-2(1H)-one supplier7-Chloro-1,6-naphthyridin-2(1H)-one uses7-Chloro-1,6-naphthyridin-2(1H)-one molecular weightprice of 7-Chloro-1,6-naphthyridin-2(1H)-one7-Chloro-1,6-naphthyridin-2(1H)-one chemical name formula of 7-Chloro-1,6-naphthyridin-2(1H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

7-Chloro-1,6-naphthyridin-2(1H)-one

CAS No. 1345091-18-0

Recommended Products