Val-Ala-PAB

Name: Val-Ala-PAB
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1343476-44-7
Cat. No. CS-0103274
Purity≥97%
MDL No.MFCD32641649

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HazMat Fee

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1343476-44-7

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Description

Val-Ala-PAB features a sterically hindered valyl-alanyl dipeptide scaffold coupled with a photolabile para-azidobenzoyl (PAB) group, enabling precise spatiotemporal control in bioconjugation workflows. This stable, bench-ready derivative facilitates efficient caging and release of bioactive molecules under UV irradiation.

Application

Val-Ala-PAB serves as a versatile dipeptide building block for peptide synthesis, featuring the valine-alanine sequence with a para-aminobenzoyl (PAB) terminus. The PAB group enhances solubility and provides a robust handle for conjugation or fluorescent tagging. Its stability under standard coupling conditions and compatibility with common protecting groups make it ideal for constructing complex peptide architectures and bioconjugates in medicinal chemistry workflows.

General Information

CAS No. 1343476-44-7
Cat. No. CS-0103274
Purity ≥97%
MDL No. MFCD32641649
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₃N₃O₃
Molecular Weight None
Synonym(s) None
SMILES CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O

Computational Chemistry Data

TPSA 104.45
LogP 0.6054
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science ADC Related Compound ADC Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

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Val-Ala-PAB

CAS No. 1343476-44-7

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