Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 2-amino-3,3,3-trifluoropropanoate hydrochloride

  • CAS No. 134297-36-2

  • Cat. No. CS-0042768
  • Molecule weight193.55
  • Purity≥95%
  • MDL No.MFCD08532471

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-3,3,3-trifluoropropanoate hydrochloride|CS-0042768

Structure of 134297-36-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 134297-36-2
  • Cat. No. CS-0042768
  • Purity ≥95%
  • MDL No. MFCD08532471
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClF₃NO₂
  • Molecular Weight 193.55
  • Synonym(s) None
  • SMILES O=C(OC)C(N)C(F)(F)F.[H]Cl

Description

Methyl 2-amino-3,3,3-trifluoropropanoate hydrochloride features a trifluoromethyl group that enhances metabolic stability and lipophilicity. The amino functionality enables direct coupling in peptide synthesis, while the hydrochloride salt ensures improved solubility and handling under standard conditions.

Application

Methyl 2-amino-3,3,3-trifluoropropanoate hydrochloride serves as a versatile building block for fluorinated bioactive molecules, enabling efficient incorporation of the trifluoromethyl group into pharmaceutical and agrochemical scaffolds. The amine functionality facilitates nucleophilic substitution, amidation, and coupling reactions, while the methyl ester permits selective reduction or hydrolysis. Its bench-stable hydrochloride salt form enhances handling and purification in standard organic workflows.

Synthesis

  • Route1
    • null|null
      103972-62-9
    • ~76%
    • In-stock
      Methyl 2-amino-3,3,3-trifluoropropanoate hydrochloride|CS-0042768
      134297-36-2

    References

    • Yagupol'skii, Yu. L.; Soloshonok, V. A.; Kukhar', V. P. Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, p. 459 - 463 Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 3 p. 517 - 521

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.4708
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 134297-36-2 sigma134297-36-2 manufacturer134297-36-2 price134297-36-2 structure134297-36-2 SDSbuy 134297-36-2134297-36-2 supplier134297-36-2 uses134297-36-2 molecular weightprice of 134297-36-2134297-36-2 chemical name formula of 134297-36-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label