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Structure of 134272-63-2
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Mal-NH-Boc features a maleimide warhead paired with a Boc-protected amine, enabling selective bioconjugation via Michael addition. This stable, bench-ready reagent integrates efficiently into peptide and protein modification workflows, offering high reactivity toward cysteine residues under physiological conditions.
Mal-NH-Boc serves as a versatile building block for the synthesis of peptide mimetics and heterocyclic scaffolds, enabling efficient introduction of a protected amine functionality. Its malonate backbone facilitates nucleophilic addition and subsequent cyclization reactions under mild conditions. The Boc group provides excellent bench stability and orthogonal deprotection compatibility, simplifying purification and downstream functionalization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: