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CS-W001157 4
Total: USD 88.00

Mal-NH-Boc

  • CAS No. 134272-63-2

  • Cat. No. CS-0115769
  • Purity≥97%
  • MDL No.MFCD03425523
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Mal-NH-Boc|CS-0115769

Structure of 134272-63-2

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Description

Mal-NH-Boc features a maleimide warhead paired with a Boc-protected amine, enabling selective bioconjugation via Michael addition. This stable, bench-ready reagent integrates efficiently into peptide and protein modification workflows, offering high reactivity toward cysteine residues under physiological conditions.

Application

Mal-NH-Boc serves as a versatile building block for the synthesis of peptide mimetics and heterocyclic scaffolds, enabling efficient introduction of a protected amine functionality. Its malonate backbone facilitates nucleophilic addition and subsequent cyclization reactions under mild conditions. The Boc group provides excellent bench stability and orthogonal deprotection compatibility, simplifying purification and downstream functionalization in multi-step syntheses.

General Information

  • CAS No. 134272-63-2
  • Cat. No. CS-0115769
  • Purity ≥97%
  • MDL No. MFCD03425523
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆N₂O₄
  • Molecular Weight 240.26
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCN1C(C=CC1=O)=O

Computational Chemistry Data

  • TPSA   75.71
  • LogP   0.4361
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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