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CS-W001157 4
Total: USD 88.00

(1S,4R)-4-Aminocyclopent-2-enecarboxylic acid

  • CAS No. 134234-04-1

  • Cat. No. CS-0157300
  • Molecule weight127.14
  • Purity≥95%
  • MDL No.MFCD00211286

*For research and further manufacturing use only, not for direct human use.

(1S,4R)-4-Aminocyclopent-2-enecarboxylic acid|CS-0157300

Structure of 134234-04-1

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General Information

  • CAS No. 134234-04-1
  • Cat. No. CS-0157300
  • Purity ≥95%
  • MDL No. MFCD00211286
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NO₂
  • Molecular Weight 127.14
  • Synonym(s) None
  • SMILES C1=C[C@@H](C[C@@H]1C(=O)O)N

Description

This cyclopentene derivative features a strategically positioned amino group and carboxylic acid moiety, enabling direct incorporation into bioactive scaffolds. The rigid, unsaturated backbone provides conformational constraint, while the amine facilitates derivatization under standard conditions. Ideal for probing structure-activity relationships in medicinal chemistry.

Application

(1S,4R)-4-Aminocyclopent-2-enecarboxylic acid serves as a valuable chiral building block for the synthesis of bioactive heterocycles and peptidomimetics. Its conjugated enamine-carboxylic acid architecture enables facile functionalization via Michael addition, electrophilic substitution, and coupling reactions. The stereochemistry at C1 and C4 ensures high diastereoselectivity in downstream transformations, while the molecule exhibits good bench stability and ease of purification, making it well-suited for medicinal chemistry campaigns and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   -0.0256
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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