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CS-W001157 4
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4-(5-Bromo-1,3,4-thiadiazol-2-yl)morpholine

  • CAS No. 1341405-19-3

  • Cat. No. CS-0186874
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(5-Bromo-1,3,4-thiadiazol-2-yl)morpholine|CS-0186874

Structure of 1341405-19-3

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General Information

  • CAS No. 1341405-19-3
  • Cat. No. CS-0186874
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BrN₃OS
  • Molecular Weight 250.12
  • Synonym(s) bromothiadiazolylmorpholine
  • SMILES C1COCCN1C2=NN=C(Br)S2

Description

4-(5-Bromo-1,3,4-thiadiazol-2-yl)morpholine features a brominated 1,3,4-thiadiazole core linked to a morpholine ring, combining electron-deficient heterocyclic character with a polar, basic nitrogen center. This structure enables robust coupling in transition-metal-catalyzed reactions and serves as a key scaffold in bioactive molecule design.

Application

4-(5-Bromo-1,3,4-thiadiazol-2-yl)morpholine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient late-stage functionalization in medicinal chemistry. The bromine atom facilitates palladium-catalyzed cross-coupling reactions, while the morpholine moiety provides solubility and hydrogen-bonding capacity. This compound exhibits excellent bench stability and is compatible with standard reaction conditions, making it ideal for modular scaffold construction in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.25
  • LogP   1.1372
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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