Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

7-Methoxy-1H-indazole

  • CAS No. 133841-05-1

  • Cat. No. CS-0043993
  • Purity≥97%
  • MDL No.MFCD08752584

*For research and further manufacturing use only, not for direct human use.

7-Methoxy-1H-indazole|CS-0043993

Structure of 133841-05-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 133841-05-1
  • Cat. No. CS-0043993
  • Purity ≥97%
  • MDL No. MFCD08752584
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 7-methoxyindazole
  • SMILES COC1=C2NN=CC2=CC=C1

Description

7-Methoxy-1H-indazole is a bench-stable heterocyclic scaffold featuring a methoxy group at the 7-position, enhancing solubility and modulating electronic properties. This electron-rich indazole core integrates readily into medicinal chemistry libraries, serving as a key building block for kinase inhibitors and bioactive molecules.

Application

7-Methoxy-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. The methoxy group enhances solubility and modulates electronic properties, while the indazole core provides a rigid, planar structure compatible with diverse coupling reactions. It functions effectively in Pd-catalyzed cross-couplings and electrophilic substitutions, offering reliable reactivity under standard conditions. Bench-stable and readily purified by recrystallization, it supports scalable synthesis of kinase inhibitors and other pharmaceutical candidates.

Synthesis

  • Route1
    • null|null
      50868-76-3
    • ~49%
    • In-stock
      7-Methoxy-1H-indazole|CS-0043993
      133841-05-1

    References

    • Sumitomo Pharmaceuticals Company, Limited Patent: EP1514869 A1, 2005 ; Location in patent: Page/Page column 83 ;
  • Route2

    References

    • Lundgren, Rylan J.; Stradiotto, Mark Angewandte Chemie - International Edition, 2010 , vol. 49, # 46 p. 8686 - 8690
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 76, p. 1176

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.91
  • LogP   1.5715
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 7-Methoxy-1H-indazole sigma7-Methoxy-1H-indazole manufacturer7-Methoxy-1H-indazole price7-Methoxy-1H-indazole structure7-Methoxy-1H-indazole SDSbuy 7-Methoxy-1H-indazole7-Methoxy-1H-indazole supplier7-Methoxy-1H-indazole uses7-Methoxy-1H-indazole molecular weightprice of 7-Methoxy-1H-indazole7-Methoxy-1H-indazole chemical name formula of 7-Methoxy-1H-indazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label