(R)-1-(2,4-Dichlorophenyl)ethan-1-amine

Name: (R)-1-(2,4-Dichlorophenyl)ethan-1-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 133773-29-2
Cat. No. CS-0099787
Purity≥97%
MDL No.MFCD06761788

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(2,4-Dichlorophenyl)ethan-1-amine|CS-0099787

Structure of 133773-29-2

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Description

(R)-1-(2,4-Dichlorophenyl)ethan-1-amine is a chiral amine featuring a sterically hindered aromatic core with two chlorine substituents in the 2,4-positions. This configuration imparts enhanced metabolic stability and selective binding affinity in asymmetric synthesis. The molecule integrates seamlessly into pharmaceutical intermediates requiring defined stereochemistry.

Application

(R)-1-(2,4-Dichlorophenyl)ethan-1-amine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of asymmetric pharmaceutical intermediates. Its bench-stable nature and tolerance to common functional groups facilitate straightforward incorporation into diverse synthetic sequences. The molecule functions effectively in amine coupling reactions and supports the construction of biologically relevant heterocyclic scaffolds via standard reductive amination or cyclization protocols.

General Information

CAS No. 133773-29-2
Cat. No. CS-0099787
Purity ≥97%
MDL No. MFCD06761788
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉Cl₂N
Molecular Weight 190.07
Synonym(s) (R)-1-(2,4-dichlorophenyl)ethanamine
SMILES C[C@@H](N)C1=CC=C(C=C1Cl)Cl

Computational Chemistry Data

TPSA 26.02
LogP 3.0131
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(2,4-Dichlorophenyl)ethan-1-amine

CAS No. 133773-29-2

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