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CS-W001157 4
Total: USD 88.00

3-Ethyl-2,5-dimethylpyrazine

  • CAS No. 13360-65-1

  • Cat. No. CS-0152557
  • Purity≥97%
  • MDL No.MFCD00053098

*For research and further manufacturing use only, not for direct human use.

3-Ethyl-2,5-dimethylpyrazine|CS-0152557

Structure of 13360-65-1

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General Information

  • CAS No. 13360-65-1
  • Cat. No. CS-0152557
  • Purity ≥97%
  • MDL No. MFCD00053098
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight 136.19
  • Synonym(s) FEMA NUMBER 3149
  • SMILES CCC1=C(C)N=CC(=N1)C

Description

3-Ethyl-2,5-dimethylpyrazine delivers a potent, roasted nut aroma profile, leveraging its fused heterocyclic core and strategically positioned alkyl substituents. This bench-stable compound integrates readily into flavor formulations requiring deep, savory notes without thermal degradation.

Application

3-Ethyl-2,5-dimethylpyrazine serves as a versatile heterocyclic building block in synthetic organic chemistry, offering enhanced stability and predictable reactivity in multi-step synthesis. Its alkylated pyrazine core facilitates functionalization at nitrogen or via electrophilic substitution, enabling access to complex scaffolds relevant in agrochemical and medicinal chemistry. The molecule exhibits favorable bench stability and ease of purification, supporting its use in scale-up processes and high-throughput screening campaigns.

Synthesis

  • Route1
    • In-stock
      3-Chloro-2,5-dimethylpyrazine|CS-W004093
      95-89-6
    • null|null
      74-96-4
    • ~80%
    • In-stock
      3-Ethyl-2,5-dimethylpyrazine|CS-0152557
      13360-65-1

    References

    • Dickschat, Jeroen S.; Wickel, Susanne; Bolten, Christoph J.; Nawrath, Thorben; Schulz, Stefan; Wittmann, Christoph European Journal of Organic Chemistry, 2010 , # 14 p. 2687 - 2695
  • Route2
    • 2,5-Dimethylpyrazine Glipizide  Impurity|CS-0229015
      123-32-0
    • null|null
      123-38-6
    • ~43%
    • In-stock
      3-Ethyl-2,5-dimethylpyrazine|CS-0152557
      13360-65-1

    References

    • Bohman, Bjorn; Berntsson, Benjamin; Dixon, Ruby C. M.; Stewart, Craig D.; Barrow, Russell A. Organic Letters, 2014 , vol. 16, # 11 p. 2787 - 2789
  • Route3
    • In-stock
      3-Chloro-2,5-dimethylpyrazine|CS-W004093
      95-89-6
    • null|null
      557-20-0
    • ~73%
    • In-stock
      3-Ethyl-2,5-dimethylpyrazine|CS-0152557
      13360-65-1

    References

    • Sato, Nobuhiro; Matsuura, Tomoyuki Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 19 p. 2345 - 2350

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.65584
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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