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CS-W001157 4
Total: USD 88.00

(S)-2-(1-Aminoethyl)phenol

  • CAS No. 133511-37-2

  • Cat. No. CS-0004264
  • Purity≥96%
  • MDL No.MFCD06761854

*For research and further manufacturing use only, not for direct human use.

(S)-2-(1-Aminoethyl)phenol|CS-0004264

Structure of 133511-37-2

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General Information

  • CAS No. 133511-37-2
  • Cat. No. CS-0004264
  • Purity ≥96%
  • MDL No. MFCD06761854
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) 2-[(1S)-1-aminoethyl]phenol
  • SMILES N[C@@H](C)C1=CC=CC=C1O

Description

(S)-2-(1-Aminoethyl)phenol is a chiral building block featuring a phenolic hydroxyl group and a stereogenic center. This configuration imparts distinct reactivity in asymmetric synthesis, enabling selective functionalization in medicinal chemistry and peptide modification workflows. The molecule demonstrates enhanced solubility in polar solvents and stability under standard bench conditions.

Application

(S)-2-(1-Aminoethyl)phenol serves as a valuable chiral building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its pendant phenolic hydroxyl and stereogenic center enable selective derivatization, while the primary amine facilitates conjugation reactions. The compound exhibits good bench stability and compatibility with standard protecting group strategies, making it well-suited for multi-step synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.4119
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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