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Structure of 1334170-03-4
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Fmoc-NH-PEG8-NHS ester enables efficient conjugation in peptide and biomolecule synthesis. This water-soluble linker features a reactive NHS ester for amine coupling, a central PEG8 spacer for enhanced solubility, and an Fmoc group for orthogonal protection. Designed for robust, site-specific labeling under standard conditions.
Fmoc-NH-PEG8-NHS ester serves as a versatile bifunctional linker for peptide and protein conjugation. The Fmoc group enables orthogonal protection during solid-phase synthesis, while the NHS ester readily reacts with primary amines under physiological conditions. The eight-ethylene glycol unit provides enhanced solubility and stability in aqueous environments, minimizing non-specific binding. This reagent facilitates efficient conjugation workflows in bioconjugate chemistry, offering reliable purification and consistent yields in antibody-drug conjugate and peptide-protein fusion applications.
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Lot numbers can be found on the outside label of a product: