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CS-W001157 4
Total: USD 88.00

Fmoc-NH-PEG8-NHS ester

  • CAS No. 1334170-03-4

  • Cat. No. CS-0107973
  • Purity≥95%
  • MDL No.MFCD21363318
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Fmoc-NH-PEG8-NHS ester|CS-0107973

Structure of 1334170-03-4

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Description

Fmoc-NH-PEG8-NHS ester enables efficient conjugation in peptide and biomolecule synthesis. This water-soluble linker features a reactive NHS ester for amine coupling, a central PEG8 spacer for enhanced solubility, and an Fmoc group for orthogonal protection. Designed for robust, site-specific labeling under standard conditions.

Application

Fmoc-NH-PEG8-NHS ester serves as a versatile bifunctional linker for peptide and protein conjugation. The Fmoc group enables orthogonal protection during solid-phase synthesis, while the NHS ester readily reacts with primary amines under physiological conditions. The eight-ethylene glycol unit provides enhanced solubility and stability in aqueous environments, minimizing non-specific binding. This reagent facilitates efficient conjugation workflows in bioconjugate chemistry, offering reliable purification and consistent yields in antibody-drug conjugate and peptide-protein fusion applications.

General Information

  • CAS No. 1334170-03-4
  • Cat. No. CS-0107973
  • Purity ≥95%
  • MDL No. MFCD21363318
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₈H₅₂N₂O₁₄
  • Molecular Weight 760.82
  • Synonym(s) None
  • SMILES O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O

Computational Chemistry Data

  • TPSA   175.85
  • LogP   2.6552
  • H_Acceptors   14
  • H_Donors   1
  • Rotatable_Bonds   30

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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