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CS-W001157 4
Total: USD 88.00

2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride

  • CAS No. 13338-49-3

  • Cat. No. CS-W021432
  • Purity≥95%
  • MDL No.MFCD04115823

*For research and further manufacturing use only, not for direct human use.

2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride|CS-W021432

Structure of 13338-49-3

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General Information

  • CAS No. 13338-49-3
  • Cat. No. CS-W021432
  • Purity ≥95%
  • MDL No. MFCD04115823
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈Cl₂N₂
  • Molecular Weight 155.03
  • Synonym(s) 5-(methylsulfonyl)-2,3-dihydro-1H-indole
  • SMILES Cl[H].ClCC1=NCCN1

Description

This imidazole derivative features a chloromethyl group enabling efficient functionalization in synthetic workflows. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating use in medicinal chemistry and peptide conjugation.

Application

2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride serves as a versatile building block for the synthesis of imidazole-containing scaffolds. Its chloromethyl group enables efficient nucleophilic substitution reactions, facilitating the construction of functionalized heterocycles. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for medicinal chemistry campaigns and process-scale applications requiring reliable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.39
  • LogP   0.6487
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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