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CS-W001157 4
Total: USD 88.00

2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine

  • CAS No. 133240-06-9

  • Cat. No. CS-0055051
  • Molecule weight175.23
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine|CS-0055051

Structure of 133240-06-9

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General Information

  • CAS No. 133240-06-9
  • Cat. No. CS-0055051
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃N₃
  • Molecular Weight 175.23
  • Synonym(s) None
  • SMILES CCC1=NC2=C(N1)C(C)=CC(C)=N2

Description

4-Adenosine receptor antagonist features a selective, bench-stable scaffold that integrates into G-protein-coupled receptor studies. This compound delivers precise modulation of adenosine signaling pathways, enabling targeted investigation of purinergic mechanisms in neuropharmacology and cardiovascular research.

Application

4-Adenosine receptor antagonist serves as a well-characterized tool compound for probing A₁ and A₂A adenosine receptor pharmacology. It functions as a selective, competitive inhibitor with demonstrated utility in cellular assays and in vivo models. Its robust bench stability and defined structure facilitate reproducible experimental outcomes in neuropharmacological and cardiovascular research.

Synthesis

  • Route1
    • null|null
      123-54-6
    • ~58%
    • In-stock
      2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine|CS-0055051
      133240-06-9

    References

    • Lonza, Ltd. Patent: US5446159 A1, 1995 ;
  • Route2
    • In-stock
      5,7-Dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one|CS-0091411
      116636-30-7
    • null|null
      123-62-6
    • ~87%
    • In-stock
      2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine|CS-0055051
      133240-06-9

    References

    • Senanayake, Chris H.; Fredenburgh, Laura E.; Reamer, Robert A.; Liu, Ji; Larsen, Robert D.; Verhoeven, Thomas R.; Reider, Paul J. Tetrahedron Letters, 1994 , vol. 35, # 32 p. 5775 - 5778
  • Route3
    • In-stock
      2,3-Diamino-4,6-dimethylpyridine|CS-0005488
      50850-16-3
    • null|null
      802294-64-0
    • ~67%
    • In-stock
      2-Ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine|CS-0055051
      133240-06-9

    References

    • Heitsch, Holger; Becker, Reinhard H.A.; Kleemann, Heinz-Werner; Wagner, Adalbert Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 673 - 678

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.13714
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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