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CS-W001157 4
Total: USD 88.00

N-Benzylacrylamide

  • CAS No. 13304-62-6

  • Cat. No. CS-0113855
  • Purity≥96%
  • MDL No.MFCD00015333

*For research and further manufacturing use only, not for direct human use.

N-Benzylacrylamide|CS-0113855

Structure of 13304-62-6

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General Information

  • CAS No. 13304-62-6
  • Cat. No. CS-0113855
  • Purity ≥96%
  • MDL No. MFCD00015333
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO
  • Molecular Weight 161.20
  • Synonym(s) Benzyl acrylamide
  • SMILES C=CC(NCC1=CC=CC=C1)=O

Description

N-Benzylacrylamide features a conjugated acrylamide warhead paired with a benzyl-substituted nitrogen, enabling efficient Michael addition reactions. This structure combines enhanced nucleophilicity with improved solubility in organic media, facilitating use in bioconjugation and polymer synthesis under standard conditions.

Application

N-Benzylacrylamide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized acrylate derivatives and heterocyclic scaffolds. Its conjugated double bond facilitates Michael additions and copolymerization reactions, while the benzyl-protected amide group offers stability and orthogonal reactivity. The molecule exhibits excellent bench stability and compatibility with diverse reaction conditions, simplifying purification and integration into multi-step syntheses.

Synthesis

  • Route1
    • null|null
      107-13-1
    • In-stock
      Benzyl alcohol|CS-4355
      100-51-6
    • ~96%
    • In-stock
      N-Benzylacrylamide|CS-0113855
      13304-62-6

    References

    • Russian Journal of Applied Chemistry, , vol. 75, # 10 p. 1718 - 1719
  • Route2
    • null|null
      79-10-7
    • null|null
      100-46-9
    • ~70%
    • In-stock
      N-Benzylacrylamide|CS-0113855
      13304-62-6

    References

    • Synthesis (Germany), , vol. 45, # 24 art. no. SS-2013-Z0527-OP, p. 3383 - 3386
  • Route3
    • null|null
      814-68-6
    • null|null
      100-46-9
    • ~95%
    • In-stock
      N-Benzylacrylamide|CS-0113855
      13304-62-6

    References

    • Angewandte Chemie - International Edition, , vol. 52, # 22 p. 5818 - 5821 Angew. Chem., , vol. 125, # 22 p. 5930 - 5933,4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.4888
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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