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CS-W001157 4
Total: USD 88.00

tert-Butyl (1S,4S)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

  • CAS No. 132666-68-3

  • Cat. No. CS-0048669
  • Molecule weight288.38
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (1S,4S)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate|CS-0048669

Structure of 132666-68-3

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General Information

  • CAS No. 132666-68-3
  • Cat. No. CS-0048669
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₄N₂O₂
  • Molecular Weight 288.38
  • Synonym(s) (1S,4S)-tert-Butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
  • SMILES CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2CC1=CC=CC=C1

Synthesis

  • Route1
    • tert-Butyl (2S,4R)-4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate|CS-0103542
      61478-27-1
    • null|null
      100-46-9
    • ~76%
    • tert-Butyl (1S,4S)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate|CS-0048669
      132666-68-3

    References

    • Jordis; Sauter; Siddiqi; Kuenburg; Bhattacharya Synthesis, 1990 , vol. 1, # 10 p. 925 - 930
  • Route2
    • null|null
      100-46-9
    • Tert-butyl (2S,4R)-4-((methylsulfonyl)oxy)-2-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate|CS-0492973
      133628-17-8
    • ~84%
    • tert-Butyl (1S,4S)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate|CS-0048669
      132666-68-3

    References

    • Huang, Xiaoguang; Chen, Dongliang; Wu, Ning; Zhang, Aiqin; Jia, Zhenhua; Li, Xingshu Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4130 - 4133

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.78
  • LogP   2.8802
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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