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CS-W001157 4
Total: USD 88.00

2-(3-Chloro-4-(Methoxycarbonyl)phenyl)acetic acid

  • CAS No. 1324054-68-3

  • Cat. No. CS-0757997
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-(3-Chloro-4-(Methoxycarbonyl)phenyl)acetic acid|CS-0757997

Structure of 1324054-68-3

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Description

This acetic acid derivative features a chlorinated aromatic ring linked to a methoxycarbonyl group, delivering enhanced solubility and stability under standard conditions. The para-substituted phenyl moiety enables efficient coupling in synthetic transformations, while the carboxylic acid functionality supports direct derivatization in pharmaceutical and agrochemical synthesis workflows.

Application

2-(3-Chloro-4-(methoxycarbonyl)phenyl)acetic acid serves as a versatile building block for pharmaceutical intermediates, enabling efficient construction of biologically relevant heterocyclic scaffolds. Its ortho-chloro and ester functionalities provide orthogonal reactivity for late-stage diversification via palladium-catalyzed cross-coupling or hydrolysis/functionalization sequences. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis in medicinal chemistry workflows.

General Information

  • CAS No. 1324054-68-3
  • Cat. No. CS-0757997
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉ClO₄
  • Molecular Weight 228.63
  • Synonym(s) None
  • SMILES COC(=O)C1=CC=C(CC(O)=O)C=C1Cl

Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.7537
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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