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CS-W001157 4
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-trityl-1H-pyrazolo[3,4-b]pyridine

  • CAS No. 1319591-26-8

  • Cat. No. CS-0153824
  • Molecule weight487.40
  • Purity≥95%
  • MDL No.MFCD26393423

*For research and further manufacturing use only, not for direct human use.

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-trityl-1H-pyrazolo[3,4-b]pyridine|CS-0153824

Structure of 1319591-26-8

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General Information

  • CAS No. 1319591-26-8
  • Cat. No. CS-0153824
  • Purity ≥95%
  • MDL No. MFCD26393423
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₁H₃₀BN₃O₂
  • Molecular Weight 487.40
  • Synonym(s) 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tritylpyrazolo[3,4-b]pyridine
  • SMILES CC1(C)C(C)(C)OB(C2=NN(C3=C2C=CC=N3)C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)O1

Description

This trityl-protected pyrazolopyridine boronate integrates seamlessly into cross-coupling workflows, offering enhanced stability and selective reactivity. The tetramethylboronate moiety enables efficient Suzuki-Miyaura coupling, while the trityl group provides robust protection for downstream transformations under standard conditions.

Application

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-trityl-1H-pyrazolo[3,4-b]pyridine serves as a robust boronate building block for palladium-catalyzed cross-coupling reactions. The trityl group provides exceptional stability and orthogonal protection, enabling selective deprotection and functionalization in complex molecule synthesis. Its compatibility with standard Suzuki-Miyaura conditions and ease of purification make it ideal for constructing bioactive heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.17
  • LogP   5.5707
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   5

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