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CS-W001157 4
Total: USD 88.00

7-(Benzyloxy)quinoline

  • CAS No. 131802-60-3

  • Cat. No. CS-0160506
  • Purity≥97%
  • MDL No.MFCD00870296

*For research and further manufacturing use only, not for direct human use.

7-(Benzyloxy)quinoline|CS-0160506

Structure of 131802-60-3

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General Information

  • CAS No. 131802-60-3
  • Cat. No. CS-0160506
  • Purity ≥97%
  • MDL No. MFCD00870296
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₃NO
  • Molecular Weight 235.28
  • Synonym(s) 7-Benzyloxyquinoline
  • SMILES C12=CC=C(OCC3=CC=CC=C3)C=C1N=CC=C2

Description

7-(Benzyloxy)quinoline features a quinoline core functionalized with a benzyloxy group at the 7-position, delivering enhanced solubility and stability in organic synthesis. This electron-rich scaffold integrates readily into pharmaceutical intermediates and ligand design, particularly in metal-catalyzed coupling reactions where its steric profile supports selective transformations under standard conditions.

Application

7-(Benzyloxy)quinoline serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through orthogonal functional group manipulation. The benzyloxy moiety provides stability under standard reaction conditions and can be selectively removed via catalytic hydrogenolysis or acidolysis. It functions effectively in coupling reactions and facilitates downstream derivatization for drug discovery applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   3.8138
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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