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CS-W001157 4
Total: USD 88.00

(S)-3-Amino-3-(4-methoxyphenyl)propanoic acid

  • CAS No. 131690-56-7

  • Cat. No. CS-0113022
  • Purity≥95%
  • MDL No.MFCD04113698

*For research and further manufacturing use only, not for direct human use.

(S)-3-Amino-3-(4-methoxyphenyl)propanoic acid|CS-0113022

Structure of 131690-56-7

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General Information

  • CAS No. 131690-56-7
  • Cat. No. CS-0113022
  • Purity ≥95%
  • MDL No. MFCD04113698
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₃
  • Molecular Weight 195.22
  • Synonym(s) None
  • SMILES O=C(O)C[C@H](N)C1=CC=C(OC)C=C1

Description

(S)-3-Amino-3-(4-methoxyphenyl)propanoic acid is a chiral building block featuring a para-methoxy-substituted phenyl group and a stereodefined amino carboxylic acid moiety. This configuration enables direct incorporation into peptidomimetics and bioactive scaffolds, offering enhanced solubility and metabolic stability in synthetic routes.

Application

(S)-3-Amino-3-(4-methoxyphenyl)propanoic acid serves as a valuable chiral building block in the synthesis of bioactive molecules, particularly those incorporating phenethylamine scaffolds. Its well-defined stereochemistry and functional group tolerance enable reliable incorporation into peptidomimetics and CNS-targeted compounds. The molecule exhibits good bench stability and facilitates straightforward purification via crystallization or ion-exchange chromatography, supporting its use in scalable medicinal chemistry campaigns.

Synthesis

  • Route1
    • null|null
      181517-88-4
    • ~96%
    • In-stock
      (S)-3-Amino-3-(4-methoxyphenyl)propanoic acid|CS-0113022
      131690-56-7

    References

    • Tetrahedron Asymmetry, , vol. 18, # 13 p. 1554 - 1566
  • Route2
    • null|null
      159848-75-6
    • ~%
    • In-stock
      (S)-3-Amino-3-(4-methoxyphenyl)propanoic acid|CS-0113022
      131690-56-7

    References

    • Tetrahedron, , vol. 50, # 31 p. 9457 - 9470
  • Route3

    References

    • Tetrahedron Asymmetry, , vol. 6, # 7 p. 1601 - 1610

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   1.1697
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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