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CS-W001157 4
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5-Bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine

  • CAS No. 1316852-65-9

  • Cat. No. CS-0050612
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine|CS-0050612

Structure of 1316852-65-9

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General Information

  • CAS No. 1316852-65-9
  • Cat. No. CS-0050612
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) 5-BROMO-2-METHYLPYRAZOLO[3,4-B]PYRIDINE
  • SMILES CN1C=C2C=C(Br)C=NC2=N1

Description

5-Bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine features a brominated pyrazolopyridine core with a methyl group at the 2-position, offering a robust scaffold for medicinal chemistry. The electron-deficient heterocycle facilitates cross-coupling reactions and integrates readily into bioactive molecules. This bench-stable compound serves as a key intermediate in targeted synthesis workflows.

Application

5-Bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine serves as a versatile building block for the synthesis of biologically active heterocycles. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the methyl substituent enhances stability and modulates electronic properties. The scaffold is well-suited for constructing complex pyrazolopyridine frameworks found in pharmaceutical intermediates, offering excellent bench stability and compatibility with standard synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   30.71
  • LogP   1.7308
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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