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CS-W001157 4
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2-Phenylethynyl-phenylamine

  • CAS No. 13141-38-3

  • Cat. No. CS-0156580
  • Purity≥97%
  • MDL No.MFCD00168849

*For research and further manufacturing use only, not for direct human use.

2-Phenylethynyl-phenylamine|CS-0156580

Structure of 13141-38-3

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General Information

  • CAS No. 13141-38-3
  • Cat. No. CS-0156580
  • Purity ≥97%
  • MDL No. MFCD00168849
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₁N
  • Molecular Weight 193.24
  • Synonym(s) 2-(2-Phenylethynyl)benzenamine
  • SMILES C1=CC=C(C=C1)C#CC2=CC=CC=C2N

Description

2-Phenylethynyl-phenylamine features a conjugated diyne-amine architecture that enables efficient coupling in cross-coupling and click chemistry applications. This electron-rich scaffold integrates readily into functionalized aromatic systems, offering enhanced stability under standard conditions for synthetic and materials chemistry workflows.

Application

2-Phenylethynyl-phenylamine serves as a versatile building block for conjugated π-systems, enabling efficient access to functionalized biaryl and heterocyclic scaffolds. Its terminal alkyne moiety facilitates copper-catalyzed coupling reactions, while the aniline functionality offers moderate basicity and ortho-directing capability in electrophilic substitutions. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6686
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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