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CS-W001157 4
Total: USD 88.00

10-Aminodecanoic acid

  • CAS No. 13108-19-5

  • Cat. No. CS-0158386
  • Purity≥95%
  • MDL No.MFCD00270349

*For research and further manufacturing use only, not for direct human use.

10-Aminodecanoic acid|CS-0158386

Structure of 13108-19-5

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General Information

  • CAS No. 13108-19-5
  • Cat. No. CS-0158386
  • Purity ≥95%
  • MDL No. MFCD00270349
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁NO₂
  • Molecular Weight 187.28
  • Synonym(s) None
  • SMILES C(CCCCC(=O)O)CCCCN

Description

10-Aminodecanoic acid features a primary amine group at the terminal position of a ten-carbon aliphatic chain, enabling facile conjugation in bioconjugation and polymer synthesis. The molecule’s hydrophobic backbone supports membrane integration, while its reactive amine facilitates coupling to carboxylated surfaces or functionalized biomolecules under mild conditions. This bifunctional architecture enables precise spatial control in surface engineering and peptide-based material design.

Application

10-Aminodecanoic acid serves as a versatile bifunctional building block for the synthesis of polymers, peptide conjugates, and bioactive molecules. Its terminal amine and carboxylic acid groups enable straightforward coupling reactions, including amidation and esterification, under standard conditions. The molecule exhibits good bench stability and facilitates purification via crystallization or ion-exchange chromatography, making it well-suited for scalable applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV; MEIJLER, Michael M.; AMARA, Neri; RAYO, Josep Patent: WO2011/1419 A1, 2011 ; Location in patent: Page/Page column 19 ;
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      10-Aminodecanoic acid|CS-0158386
      13108-19-5

    References

    • Kogyo Kagaku Zasshi, , vol. 57, p. 769 Chem.Abstr., , p. 10234
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      91017-32-2
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    • In-stock
      10-Aminodecanoic acid|CS-0158386
      13108-19-5

    References

    • US2862940 , ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   2.1505
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   9

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