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CS-W001157 4
Total: USD 88.00

(1,3-Dimethyl-1H-indazol-5-yl)boronic acid

  • CAS No. 1310404-48-8

  • Cat. No. CS-0053670
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1,3-Dimethyl-1H-indazol-5-yl)boronic acid|CS-0053670

Structure of 1310404-48-8

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General Information

  • CAS No. 1310404-48-8
  • Cat. No. CS-0053670
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BN₂O₂
  • Molecular Weight 190.01
  • Synonym(s) 1,3-Dimethylindazole-5-boronic acid
  • SMILES CN1N=C(C)C2=C1C=CC(=C2)B(O)O

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering functionalized indazoles with high efficiency. The dimethyl substitution enhances solubility and stability under standard conditions, enabling reliable use in synthetic workflows.

Application

(1,3-Dimethyl-1H-indazol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. The indazolyl scaffold provides enhanced metabolic stability and favorable physicochemical properties, making it valuable for medicinal chemistry applications. The boronic acid moiety offers excellent bench stability, compatibility with diverse reaction conditions, and straightforward purification via standard chromatographic or crystallization methods.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -0.43848
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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