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CS-W001157 4
Total: USD 88.00

(1,5-Dimethyl-1H-indazol-6-yl)boronic acid

  • CAS No. 1310383-98-2

  • Cat. No. CS-0039020
  • Purity≥98%
  • MDL No.MFCD12028659

*For research and further manufacturing use only, not for direct human use.

(1,5-Dimethyl-1H-indazol-6-yl)boronic acid|CS-0039020

Structure of 1310383-98-2

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General Information

  • CAS No. 1310383-98-2
  • Cat. No. CS-0039020
  • Purity ≥98%
  • MDL No. MFCD12028659
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BN₂O₂
  • Molecular Weight 190.01
  • Synonym(s) 6-Borono-1,5-dimethyl-1H-indazole
  • SMILES OB(C1=CC2=C(C=C1C)C=NN2C)O

Description

This boronate moiety integrates a 1,5-dimethyl-1H-indazol-6-yl scaffold, delivering enhanced stability and solubility in polar solvents. The electron-rich indazole core enables efficient coupling in Suzuki-Miyaura reactions under standard conditions. Bench-stable and moisture-tolerant, this reagent streamlines access to functionalized heteroaromatic architectures in medicinal chemistry and materials science.

Application

(1,5-Dimethyl-1H-indazol-6-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. The indazolyl scaffold imparts enhanced metabolic stability and favorable physicochemical properties, making it valuable for medicinal chemistry campaigns. Its boronic acid functionality exhibits excellent bench stability, tolerates common functional groups, and facilitates straightforward purification—ideal for iterative synthesis and library generation in drug discovery workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -0.43848
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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