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Structure of 1309788-50-8
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3-Iodo-6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazole is a sterically hindered heterocyclic iodide featuring a bench-stable indazole core. This compound integrates readily into cross-coupling reactions due to its reactive iodine handle and electron-deficient aromatic system. The dimethyl substitution enhances solubility and stability in organic media, facilitating efficient incorporation into complex molecular architectures under standard conditions.
3-Iodo-6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazole serves as a versatile building block for the synthesis of biologically active heterocycles. The iodine substituent enables palladium-catalyzed cross-coupling reactions, facilitating C–C bond formation under mild conditions. Its saturated indazole core offers enhanced metabolic stability and favorable solubility compared to aromatic analogs. Bench-stable and readily purified by flash chromatography, it functions effectively in late-stage functionalization and medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: