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CS-W001157 4
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4,4-Dimethyl-1,4-azasilinane hydrochloride

  • CAS No. 130596-62-2

  • Cat. No. CS-0043662
  • Molecule weight165.74
  • Purity≥97%
  • MDL No.MFCD28399395

*For research and further manufacturing use only, not for direct human use.

4,4-Dimethyl-1,4-azasilinane hydrochloride|CS-0043662

Structure of 130596-62-2

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General Information

  • CAS No. 130596-62-2
  • Cat. No. CS-0043662
  • Purity ≥97%
  • MDL No. MFCD28399395
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆ClNSi
  • Molecular Weight 165.74
  • Synonym(s) None
  • SMILES C[Si]1(C)CCNCC1.[H]Cl

Description

4,4-Dimethyl-1,4-azasilinane hydrochloride is a bench-stable, moisture-tolerant silacycle featuring a tertiary amine nitrogen flanked by two methyl-substituted silicon centers. This sterically shielded structure enhances solubility in polar organic solvents and facilitates straightforward incorporation into synthetic sequences requiring mild nucleophilic reactivity. The hydrochloride salt form ensures high purity and ease of handling during routine laboratory operations.

Application

4,4-Dimethyl-1,4-azasilinane hydrochloride serves as a stable, bench-friendly silane equivalent for the introduction of Si–CH₂–CH₃ and Si–CH₃ groups in synthetic workflows. Its tertiary amine functionality enables efficient nucleophilic activation, while the sterically protected silicon center enhances functional group tolerance. This reagent facilitates direct silylation of alcohols, amines, and carboxylic acids under mild conditions, offering a practical alternative to traditional hydrosilylation protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.7198
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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