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CS-W001157 4
Total: USD 88.00

(2-Bromophenyl)-phenylmethanone

  • CAS No. 13047-06-8

  • Cat. No. CS-0037116
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Bromophenyl)-phenylmethanone|CS-0037116

Structure of 13047-06-8

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General Information

  • CAS No. 13047-06-8
  • Cat. No. CS-0037116
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉BrO
  • Molecular Weight 261.11
  • Synonym(s) 2-Bromobenzophenone
  • SMILES C1=CC=C(C=C1)C(=O)C2=C(C=CC=C2)Br

Description

This aryl ketone features a brominated phenyl ring attached to a benzoyl group, enabling direct incorporation into cross-coupling reactions. The ortho-bromine facilitates palladium-catalyzed transformations while maintaining stability under standard reaction conditions.

Application

(2-Bromophenyl)-phenylmethanone serves as a versatile aryl ketone building block for the synthesis of biaryl systems and heterocyclic scaffolds. Its brominated aryl ring enables palladium-catalyzed cross-coupling reactions, while the benzoyl functionality offers stability and compatibility with standard organic transformations. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      98-88-4
    • In-stock
      (2-Bromophenyl)boronic acid|CS-W000903
      244205-40-1
    • ~88%
    • In-stock
      (2-Bromophenyl)-phenylmethanone|CS-0037116
      13047-06-8

    References

    • Arkivoc, , vol. 2013, # 4 p. 251 - 271
  • Route2
    • 2-Aminobenzophenone Nepafenac Impurity|CS-0229200
      2835-77-0
    • ~70%
    • In-stock
      (2-Bromophenyl)-phenylmethanone|CS-0037116
      13047-06-8

    References

    • Angewandte Chemie - International Edition, , vol. 44, # 11 p. 1654 - 1657
  • Route3
    • (2-Bromophenyl)(phenyl)methanol|CS-0668129
      59142-47-1
    • ~89%
    • In-stock
      (2-Bromophenyl)-phenylmethanone|CS-0037116
      13047-06-8

    References

    • Journal of Organic Chemistry, , vol. 79, # 5 p. 2059 - 2074

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H411
Precautionary Statements : P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.6801
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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