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CS-W001157 4
Total: USD 88.00

2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine

  • CAS No. 128430-66-0

  • Cat. No. CS-0444311
  • Molecule weight239.62
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine|CS-0444311

Structure of 128430-66-0

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General Information

  • CAS No. 128430-66-0
  • Cat. No. CS-0444311
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉ClF₃NO
  • Molecular Weight 239.62
  • Synonym(s) 2-Chloromethyl-3-methyl-4-trifluoroethylpyridine
  • SMILES CC1=C(CCl)N=CC=C1OCC(F)(F)F

Synthesis

  • Route1
    • (3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanol|CS-0133683
      103577-66-8
    • ~%
    • 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine|CS-0444311
      128430-66-0

    References

    • Journal of Medicinal Chemistry, , vol. 35, # 3 p. 438 - 450
  • Route2
    • null|null
      103577-61-3
    • ~%
    • 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine|CS-0444311
      128430-66-0

    References

    • Synthetic Communications, , vol. 32, # 8 p. 1211 - 1217
  • Route3
    • (3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl acetate|CS-0536259
      112525-75-4
    • ~%
    • 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine|CS-0444311
      128430-66-0

    References

    • Journal of Medicinal Chemistry, , vol. 35, # 3 p. 438 - 450

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   3.06992
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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