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CS-W001157 4
Total: USD 88.00

Sodium 2,2-difluoropropanoate

  • CAS No. 1281943-34-7

  • Cat. No. CS-0132392
  • Molecule weight132.04
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Sodium 2,2-difluoropropanoate|CS-0132392

Structure of 1281943-34-7

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General Information

  • CAS No. 1281943-34-7
  • Cat. No. CS-0132392
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃F₂NaO₂
  • Molecular Weight 132.04
  • Synonym(s) None
  • SMILES CC(F)(F)C(O[Na])=O

Description

Sodium 2,2-difluoropropanoate is a bench-stable, moisture-tolerant fluorinated carboxylate salt featuring a geminal difluoro substitution that imparts enhanced electrophilicity. This structural motif enables efficient coupling reactions in synthetic organic chemistry, particularly in the construction of fluorinated building blocks for medicinal and agrochemical applications.

Application

Sodium 2,2-difluoropropanoate serves as a stable, bench-ready source of the difluoromethyl carboxylate moiety, enabling efficient incorporation of fluorinated building blocks in synthetic routes. It functions as a key precursor in the construction of trifluoromethylated heterocycles and fluorinated pharmaceutical intermediates, demonstrating excellent functional group tolerance and compatibility with standard coupling and nucleophilic substitution protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.2683
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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