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Structure of 128073-09-6
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3-Chloro-5-methoxypicolinic acid features a strategically positioned chloro group and methoxy substituent on the picolinic acid scaffold, enhancing electronic modulation and metabolic stability. This combination improves binding affinity in targeted receptor interactions and supports efficient derivatization under standard coupling conditions.
3-Chloro-5-methoxypicolinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of halogen and ester functionalities into bioactive heterocycles. Its ortho-halogenated pyridine core facilitates palladium-catalyzed cross-coupling reactions, while the methoxy group offers orthogonal handle for subsequent derivatization. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, facilitating efficient access to complex scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: