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2-(Aminomethyl)-5-hydroxypyridine HCl

  • CAS No. 1276056-66-6

  • Cat. No. CS-0208617
  • Molecule weight160.60
  • Purity≥97%
  • MDL No.MFCD17214179

*For research and further manufacturing use only, not for direct human use.

2-(Aminomethyl)-5-hydroxypyridine HCl|CS-0208617

Structure of 1276056-66-6

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General Information

  • CAS No. 1276056-66-6
  • Cat. No. CS-0208617
  • Purity ≥97%
  • MDL No. MFCD17214179
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉ClN₂O
  • Molecular Weight 160.60
  • Synonym(s) 6-(Aminomethyl)pyridin-3-ol hydrochloride
  • SMILES C1=CC(=CN=C1CN)O.Cl

Description

2-(Aminomethyl)-5-hydroxypyridine HCl features a pyridine core bearing a hydroxyl group at the 5-position and a primary amine tethered via a methylene linker. This bifunctional scaffold enables straightforward conjugation and integration into bioactive molecules, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

2-(Aminomethyl)-5-hydroxypyridine HCl serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based pharmacophores. The compound features a hydroxyl group at the 5-position and a primary amine tethered via a methylene linker, offering orthogonal reactivity for conjugation and derivatization. Its hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.6677
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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